Thioptea
WebThiotepa (N,N′,N″-triethylenethiophosphoramide, MW 189) is an older chemotherapeutic anticancer agent that acts by alkylating DNA and is prescribed for treating solid tumors and various leukemias often at high doses and in combination with other anticancer agents. Mass spectrometric methods were developed for characterizing the structure of thiotepa … WebThiotepa may be given rapidly intravenously in doses of 0.3–0.4 mg/kg at intervals of 1–4 weeks. The drug has also been given intravenously in doses of 0.2 mg/kg or 6 mg/m 2 daily for 4 or 5 days at intervals of 2–4 weeks. …
Thioptea
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WebThiotepa C6H12N3PS CID 5453 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity … WebAdvances in Biomarker Sciences and Technology (Jan 2024) . Therapeutic capability of selected medicinal plants' bioactive constituents against the mutant ovarian TP53 gene; a …
WebThiotepa can damage sperm or cause sterility in men. It can temporarily or permanently stop the menstrual cycle in women. If you are pregnant OR plan to have children in the future, discuss this with your physician before receiving treatment. Use an effective form of birth control while you or your partner is being treated with Thiotepa. WebApr 1, 2024 · Thiotepa injection is used to lower risk of graft rejection when used with other medicines (eg, high-dose busulfan, cyclophosphamide) as a preparative regimen for stem …
WebThiotepa is a type of chemotherapy. It works by slowing or stopping the growth of cancer cells. It is usually used in combination with other medicines. Patients will have regular blood draws to check blood counts and monitor liver and kidney function. WebThiotepa is a type of chemotherapy. It works by slowing or stopping the growth of cancer cells. It is usually used in combination with other medicines. Patients will have regular …
WebJun 4, 2024 · TBF-MAC included more intensive combinations of thiotepa (5 mg/kg/day for 1 or 2 days), fludarabine (30 to 40 mg/m²/day for 4 days), and i.v. busulfan (130 mg/m²/day for 3 or 4 days). We did not use pharmacokinetic dosages of busulfan. GVHD prophylaxis was based on PT-Cy (50 mg/kg on days +3 and +4) and cyclosporine A plus mycophenolate ...
WebThiotepa can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others (such as chickenpox , measles , flu ). boating direction termsWebprecautions should be followed when handling thiotepa; if skin contact occurs, wash the area thoroughly with soap and water; if mucous membrane contact occurs, flush thoroughly with water. 2. Carcinogenicity: Thiotepa is carcinogenic. 2. Mutagenicity: Mutagenic in Ames test and mammalian in vitro mutation test. 2 Thiotepa is clastogenic in ... boating distancesWebThiotepa is used to treat certain types of ovarian cancer (cancer that begins in the female reproductive organs where eggs are formed), breast, and bladder cancer. It is also used to … clift meadow bramleyWebThiotepa impaired fertility in male mice at PO or IP doses ≥0.7 mg/kg (2.24 mg/m2), approximately 12-fold less than the maximum recommended human therapeutic dose based on body-surface area. Thiotepa (0.5 mg) inhibited implantation in female rats when instilled into the uterine cavity. Thiotepa interfered with spermatogenesis in mice at IP cliftleigh to torontohttp://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Thiotepa_monograph_1June2013_formatted.pdf clift meaningWebThiotepa may be given into the bladder to treat bladder cancer. Thiotepa has also been used with other medications to prevent rejection of a stem cell transplant. HOW TO USE: This … boating distress flagWebDec 12, 2024 · Signs of liver problems like dark urine, tiredness, decreased appetite, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight. boating dishes